Some Question Just for practice

Hi Folks ! Here is my another  post  with another important clue . Its practice . I would recommend you to do practice the question answers as much as you can . Study and practice . This will help you in examination hall , where most of the students complains   about not enough time  I posting some questions here , these are just for practice  and do no think. Please study these 30 question and post your answers



Thanks !

1.      which of the following functional groups are tertiary hydroxyl group

A.    ..

B.     ..

C.    ..

D.    ..

E.     ..

2.      which of the following groups have geometrical isomers:

A.    Hexane and cyclohexane

B.     Pentane and pentene

C.    Butene and 2-Butene

D.    Benzene and hexane

E.     Non of the above

3.      Which of the following statements concerning cytochrome enzyme are CORRECT?

                                                 I.      The CYP7, CYP11, CYP27 are cytochrome enzyme responsible for cholesterol metabolism.

                                              II.      CYP3A is most common metabolizing enzyme in the body.

                                           III.      CYP3A does phase I reductive reactions.

A.    I Only

B.     III Only

C.    I and II Only

D.    II And III Only

E.     All Of the above

4.      The following statements are CORRECT about a muscarinic antagonist Atropine :

A.    Atropine structure contain piperidine a pyridines rings.

B.     Piperidine and pyrrolidine

C.    Pirmidine and pyrrolidine

D.    Quasi ring structure but not tertiary amine

E.     Pyridine and Quasi rings structure.

5.      If a structure of drug contain 3 sterogenic centers “chiral centers”, their will be how many isomers possible for this structure?

A.    8

B.     21

C.    3

D.    2

E.     12

6.      1-propanol and 2-propanol they are:

A.    Conformational Isomer

B.     Geometric Isomer

C.    Constitutional Isomer

D.    Diasteroisomers Isomer

E.     Enatiomers Isomer

7.      hexane and 2-methyl pentane are:

A.    Conformational Isomer

B.     Geometric Isomer

C.    Constitutional Isomer

D.    Diasteroisomers Isomer

E.     Enatiomers Isomer

8.      All the following statements are CORRECT about Enatiomers EXCEPT:

A.    Enatiomers are optical isomers that are mirror images of another

B.     Enatiomers are rotate pan of polarized light in clockwise direction are know as dextrorotatory (D) or (+)

C.    Enatiomers have identical physical and chemical properties

D.    Enatiomers are rotate plan polarized light in anticlockwise direction are know as levorotatory.

E.     100% mixture of (D) or (L) Enatiomers is called racemic mixture.

9.      All of the following statements are CORRECT about Diasteroisomers EXCEPT:

A.    Diasteroisomers are neither mirror image no superimposible images

B.     Diasteroisomers must contain at least two chiral centers

C.    Diasteroisomers differ in properties such as solubility, volatility and melting point

D.    Diasteroisomers contain different physical and chemical properties

E.     Diasteroisomers contain non superimposible mirror images

10.  Conversion of tetracycline to 4-epi tetracycline process in known as:

A.    Isomerization

B.     Epimerization

C.    Conversion

D.    Substitution

E.     Chemical reaction

11.  D(+) Lactic acid and L (-) Lactic acid are:

A.    Diasteroisomers

B.     Enatiomers

C.    Constitutional isomers

D.    Geometrical isomers

E.     Stereoisomer

12.  Result of restriction around double bond a result in the following isomers:

A.    Diasteroisomers

B.     Enatiomers

C.    Constitutional isomers

D.    Conformational isomers

E.     Geometrical isomers

13.  Metabolic reactions that may be affected by a protein deficiency diet include:

                                      I.      Oxidative Reaction

                                   II.      Hydrolysis

                                III.      Glycine Conjugation

A.    I Only

B.     III Only

C.    I and II Only

D.    II And III Only

E.     All Of the above

14.  In amino acid conjugation which of the following reactions are involved:

A.    Amino acid + Alcohol

B.     Amino acid + Amino acid

C.    Amino acid + Glycine

D.    Glycine + Alcohol

E.     Amino Acid + Glutamine

15.  Which is strongest Base:

A.    ----

B.     ----

C.    ----

D.    ---

E.     ---

16.  CYT P450 is :

A.    Enzyme

B.     Vitamin

C.    Neurotransmitter

D.    Catalyst

E.     Amino acid

17.  Where is the hydrolysis occur:

A.    –

B.     –

C.    –

D.    –

E.     –

18.  Where is the hydrolysis occur:

A.    E

B.     E

C.    E

D.    e

E.     E

19.  All the following are metabolic enzymes EXCEPT:

A.    CYP 450

B.     CYP 3A4

C.    CYP 0

D.    CYP 1A4

E.     CYP 2A1

20.  All the following are cytochrome enzymes metabolize drug xenobiotics (Biological Product) EXCEPT:

A.    CYP 450

B.     CYP 3A4

C.    CYP 17

D.    CYP 1A4

E.     CYP 2A1

21.  Antidepressants are metabolized by:

A.    CYP 450 And CYP 1A2

B.     CYP 3A4 And CYP 1A2

C.    CYP 2D6 And CYP 1A2

D.    CYP 1A4 And CYP 1A2

E.     CYP 2A1 And CYP 1A2

22.  Statins are metabolized by:

A.    CYP 17

B.     CYP 1A2

C.    CYP 3A

D.    CYP 2A1

E.     CYP 450

23.  Benzodiazepines Are metabolized be:

A.    CYP 17

B.     CYP 1A2

C.    CYP 3A

D.    CYP 2A1

E.     CYP 450

24.  Grapefruit juice inhibit the following enzyme:

A.    CYP 17

B.     CYP 1A2

C.    CYP 3A4

D.    CYP 2A1

E.     CYP 450

25.  Smoking induces the following Cytochrome enzyme:

A.    CYP 17

B.     CYP 1A2

C.    CYP 3A

D.    CYP 2A1

E.     CYP 450

26.  Which enzyme does glucourdiation reaction:

A.    UDPGA

B.     ….

C.    ….

D.    ….

E.     ….

27.  What characteristics of an organic compound allow it to undergo conjugation with glutathione?

A.    Electrophilic functional groups

B.     …

C.    …

D.    …

E.     …

28.  Amino acids conjugation involve the following group:

A.    Amino acid and glycin

B.     Amino acid and glutamine

C.    Amino acid

D.    Activated amino acid

E.     Amino acid and glutamine

29.  Glutamine Conjugation very important in preventing toxicity of variety of drugs, toxic products are excreted as:

A.    S-adonozyl transferase

B.      Glutamic acid

C.    Mercaptoric acid

D.    Amino acid

E.     Sulfadryl groups

30.  which of the following statements about drugs metabolism correct:

A.    drug metabolizing enzyme are found only in liver

B.     all metabolites are pharmacologically inactive

C.    phase I metabolite can cross cell membrane

D.    all drugs are catalyzed by cytochrome

E.     commonly one metabolite is excreted for each drug administered