Few More questions
2
1. Proposed cellular
mechanisms of theophylline's action include:
A. translocation of
intracellular calcium
B. those mediated by
increasing accumulation of intracellular cyclic AMP
C. those mediated by
blockade of receptors for adenosine
D. those mediated by
xanthine oxidase inhibition
1. A,B,C
2. A,C
3. B,D
4. D only
5. All of the above
Answer: 2
2. Drugs that may
decrease theophylline clearance include:
A.
cimetidinE
B.
ranitidine
C.
ciprofloxacin
D. phenytoin
1. A,B,C
2. A,C
3. B,D
4. D only
5. All of the above
answer: 5
3. Theophylline
clearance may be reduced by:
1. phenobarbital
2. warfarin
3. tobacco smoking
4. phenytoin
5. ciprofloxacin
answer: 5
4. Factors which are
important to consider in selecting a maintenance dose of
theophylline in a
patient include all of the following EXCEPT:
1. smoking history
2. concomitant
medication administration
3. presence of
congestive heart failure or cor pulmonale
4. presence of hepatic
failure
5. presence of renal
insufficiency
answer: 5
5. Manifestations of
theophylline toxicity may include all of the following
EXCEPT:
1. tremors
2. seizures
3. tachyarrhythmias
4. vomiting
5. hyperkalemia
answer: 2
6. In the case of an
oral overdose of theophylline, clearance may be enhanced by:
1. induction of emesis
2. oral pulse dose
charcoal
3. administration of
cimetidine
4. lavage of nasogastric
contents
5. forced diuresis
answer: 4
7. Regarding its
actions, cromolyn is best described as:
1. bronchodilator
2. anticholinergic
3. beta agonist
4. inhibitor of mast
cell degranulation
5. glucocorticoid
Answer: 4
8. Beta-2 selective
adrenergic agonists include all EXCEPT:
1. terbutaline
2. albuterol
3. metaproterenol
4. isoproterenol
5. pirbuterol
Answer: 5
9. Adverse effects of
beta-2 adrenergic bronchodilators include all of the
following EXCEPT:
1. nervousness
2. headache
3. tachycardia
4. tremulousness
5. lethargy
Answer: 4
10. Which of the
following work through cholinergic receptor antagonism?
1. isoetharine
2. cromolyn
3. ephedrine
4. ipratropium
5. salmeterol
Answer: 1
11. Which of the
following pharmacologic agents antagonize adenosine?
1. theophylline
2. glucocorticoids
3. cromolyn sodium
4. propranolol
5. terbutaline
Answer: 2
12. Theophylline,
ethacrynic acid, and furosemide:
1. interfere with active
renal tubular reabsorption of sodium
2. increase urine volume
3. are not effective in
the treatment of congestive heart failure
4. decrease excretion of
sodium in the uriNE
5. may precipitate in
renal tubules and cause acute angiospastic necrosis
Answer: 4
13. An 81-year-old
female with arteriosclerotic heart disease and pulmonary
emphysema was found to
have significant bronchospasm. Her physician prescribed
theophylline 400 mg
every 12 hours. All of the following toxicities may be
observed EXCEPT:
1. cardiac arrhythmias
2. nausea and vomiting
3. agitation
4. sodium and water
retention
5. tremulousness
Answer: 5
14. When comparing the
relative adrenergic effects of the following drugs, the one
which would have the
least 2 (bronchodilatation) effect at normal doses is:
1.
terbutaline
2.
epinephrine
3.
isoproterenol
4.
isoetharine
5.
norepinephrine
No comments:
Post a Comment