More Practice Questions
In Pharmacy Exams either
it is pharmacy college exams or professional bodies exams accuracy and speed is very important .Along with
right answers you have to make sure that you are not wasting your time on questions,
about which you have no clue . So Just jump to next, so that you are not
running out of time. At the end, again I would suggest that practice these
questions and compare your answers with some authenticated sources.Another Important thing is that study all other options , why they can not be answers .You will build your knowledge base
Answer: 3
1. Which of
the following substances has its major activity as a saline cathartic ?
1. Sodium bicarbonate
2. Methylcellulose
3. Sodium phosphate
4. Castor oil
5. Mineral oil
Answer: 4
2. The correct statement
regarding sucralfate:
1. Pharmacologic action
is to reduce gastric acid secretion by antagonizing Gatrin
2. Enhances N+-K+ ATPase
3. Antagonizes
acetylcholine
4. Most common side
effects is constipation
5. Increases gastric
motility
Answer: 4
3. Correct statement
regarding metoclopramide:
1. Central nervous
system dopamine receptor agonist
2. Peripheral blockage
of acetylcholine at muscarinic synapse
3. Decreases lower
esophageal sphincter pressure
4. Adverse effects
include dystonic or extrapyramidal effects
5. Increases motility of
colon
Answer: 5
4. In general,
mechanisms of laxation include:
1. Adding bulk to the
stool
2. Increasing
peristaltic activity
3. Emulsifying aqueous
and fatty substances with stool
4. Lubricating the
passage of stool
5. All of the above
Answer: 1
5. Appropriate
indications for and/or uses of laxatives include:
A. prevent straining at
the stool in patients with cardiovascular disease
B. bulk forming agents
for diverticular disease
C. treatment of drug
overdose
D. to induce daily bowel
movements in normal healthy individuals
1. A, B, C
2. A, C
3. B, D
4. D only
5. All of the above
Answer: 1
6. Which of the
following substances is most likely to cause systemic alkalosis?
1. Sodium bicarbonate
2. Methylcellulose
3. Sodium phosphate
4. Castor oil
5. Mineral oil
Answer: 4
7. Saline cathartics,
such as sodium sulfate or magnesium sulfate:
1. are safe in patients
with renal failure
2. are readily absorbed
from the gastrointestinal tract
3. are slower acting
than bulk-forming laxatives
4. act by increasing
intestinal volume, hence stimulating peristaltic action
5. lower the surface
tension of the feces to facilitate fecal hydration
Answer: 5
8. Adverse effect(s) of
laxatives:
1. Electrolyte
disturbances (hypernatremia, hypokalemia)
2. Dehydration
3. spastic colitis with
stimulant laxatives
4. gastrointestinal
obstruction with bulk forming agents
5. All of the above
Answer: 5
9. In esophagitis ,
elevation of the head of the bed, abstinence from ethanol and
Tobacco, and small
frequent meals are all useful adjunctive therapeutic measures
Other useful therapy may
include all of the following EXCEPT:
1. omeprazole
2. metoclopramide
3. bethanechol
4. cimetidine
5. amitriptyline
Answer: 2
10. Drug which exerts
anti-peptic ulcer effects through histamine-2 receptor
Antagonism:
1. sucralfate
2. ranitidine
3. metoclopramide
4. omeprazole
5. misoprostol
Answer: 5
11. The substance which
is principally an emollient laxative is:
1. bran
2. methylcellulose
3. magnesium hydroxide
4. phenolphthalein
5. mineral oil
Answer: 3
12. Laxatives may aid in
the treatment of portal systemic encephalopathy by:
1. increasing stool pH
2. increasing coliform
bacteria
3. decreasing protein
contact time with GI mucosa
4. All of the above
5. 1,3
Answer: 5
13. Agents of potential
use in peptic ulcer disease include:
1. muscarinic
antagonists
2. proton pump
inhibitors
3. antacids
4. prostaglandins
5. All of the above
Answer: 5
14. The physician must
always be aware of possible drug interactions. Aluminum
hydroxide antacids tend
to interfere with the gastrointestinal absorption of:
1. cephalexin
2. penicillin G
3. erythromycin
4. chloramphenicol
5. tetracycline
Answer: 4
15. Prostaglandins E2
inhibit the secretion of gastric acid and stimulate the
secretion of mucus. One
adverse effect limiting the wide use of
prostaglandins for
gastric disease is:
1. headache
2. thrombocytopenia
3. gynecomastia
4. diarrhea
5. seizures
Answer: 3
16. An agent which
promotes defecation without increasing peristalsis is:
1. castor oil
2. phenolphthalein
3. docusate sodium
4. cascara
5. milk of magnesia
Answer: 4
17. Cimetidine reduces
the clearance of all of the following EXCEPT:
1. theophylline
2. phenytoin
3. warfarin
4. digoxin
5. quinidine
Answer: 5
18. The basic approach
to the patient with either acute or chronic hepatic
encephalopathy is aimed
at reducing the ammonia load presented to the central
nervous system.
Elimination of protein from the diet, cathartics, enemas,
neomycin and lactulose
(a disaccharide) have been used to accomplish this
goal. Correct statements
regarding the mechanism of action of lactulose
include:
1. reduced fecal Ph by
the breakdown products of lactulose leads to reduced
ammonia absorption via
non-ionic diffusion
2. the decreased fecal
pH increases bacterial assimilation of ammonia
3. lactulose induces an
osmotic diarrhea which diminishes fecal stasis and
reduces nitrogenous
substrates
4. All of the above
5. 1,3
Answer: 5
19. Antacids having a
relatively non-systemic effect include:
1. aluminum hydroxide
2. sodium bicarbonate
3. calcium carbonate
4. All of the above
5. 1 and 3
Answer: 4
20. Which of the following
substances has its major activity as an stimulant
cathartic?
1. sodium bicarbonate
2. methylcellulose
3. sodium citrate
4. castor oil
5. mineral oil
Answer: 3
21. One mechanism to
reduce gastric acid secretion is by blocking the H+-Na+
ATPase pump in the
parietal cell. One drug that has this pharmacologic action
is:
1. misoprostol
2. pirenzepine
3. omeprazole
4. serotonin
5. isoniazid
Answer: 1
22. The amount of
sodium, phosphate or magnesium contained in an antacid should be
assessed when selecting
an antacid for patients with:
A. renal insufficiency
B. congestive heart
failure
C. ascites
D. peptic ulcer disease
1. A,B,C
2. A,C
3. B,D
4. D only
5. All of the above
Answer: 3
23. The concomitant
administration of calcium and/or magnesium antacids to
patients receiving one
of the tetracycline drugs may have which of the
following effects upon
the action of the tetracycline:
1. enhances the action
2. causes no significant
change
3. decreases the action
4. increases toxicity
5. suppresses
hypersensitivity reactions
Answer: 2
24. Pharmacologic
effects of antacids include:
A. increase gastric pH
B. reversible
inactivation of pepsin at pH > 6
C. increase or decrease
gastric motor activity
D. decrease lower
esophageal pressure
1. A,B,C
2. A,C
3. B,D
4. D only
5. All of the above.